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Masashi Akiyama Selected Research

Palmoplantar Keratoderma (Keratosis Palmaris et Plantaris)

1/2022Differential Pathomechanisms of Desmoglein 1 Transmembrane Domain Mutations in Skin Disease.
10/2017Striate Palmoplantar Keratoderma Showing Transgrediens in a Patient Harbouring Heterozygous Nonsense Mutations in Both DSG1 and SERPINB7.
6/2007Keratin 1 gene mutation detected in epidermal nevus with epidermolytic hyperkeratosis.

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Masashi Akiyama Research Topics

Disease

29Ichthyosis (Xeroderma)
01/2022 - 11/2003
21Dermatomyositis (Dermatopolymyositis)
02/2022 - 01/2011
19Neoplasms (Cancer)
11/2022 - 06/2008
15Psoriasis (Pustulosis Palmaris et Plantaris)
01/2022 - 02/2014
15Lamellar Ichthyosis (Harlequin Ichthyosis)
08/2015 - 07/2005
13Myositis (Idiopathic Inflammatory Myopathies)
02/2022 - 07/2012
11Atopic Dermatitis (Atopic Eczema)
09/2020 - 02/2007
10Melanoma (Melanoma, Malignant)
01/2020 - 01/2011
8Polymyositis
02/2022 - 06/2013
8Inflammation (Inflammations)
01/2022 - 01/2008
7Systemic Scleroderma (Systemic Sclerosis)
11/2022 - 07/2013
7Epidermolytic Hyperkeratosis (Bullous Congenital Ichthyosiform Erythroderma)
09/2014 - 02/2002
6Systemic Lupus Erythematosus (Libman-Sacks Disease)
09/2021 - 03/2015
6Bullous Pemphigoid (Pemphigoid)
11/2018 - 03/2005
6Ichthyosis Vulgaris (Dominant Ichthyosis Vulgaris)
07/2014 - 02/2007
6Epidermolysis Bullosa Dystrophica (Dystrophic Epidermolysis Bullosa)
11/2012 - 01/2006
5Interstitial Lung Diseases (Interstitial Lung Disease)
02/2022 - 01/2011
5Pemphigus (Pemphigus Vulgaris)
10/2020 - 01/2013
5Chanarin-Dorfman Syndrome
02/2016 - 11/2003
5Autoimmune Diseases (Autoimmune Disease)
03/2015 - 03/2007
4Rheumatic Diseases (Rheumatism)
11/2022 - 01/2013
4Squamous Cell Carcinoma (Epidermoid Carcinoma)
05/2022 - 08/2013
4Fever (Fevers)
02/2022 - 09/2016
4Skin Diseases (Skin Disease)
01/2022 - 03/2007
4Pruritus (Itching)
09/2020 - 01/2008
4Epidermolysis Bullosa Simplex (Epidermolysis Bullosa Herpetiformis Dowling Meara)
09/2013 - 03/2010
4Epidermolysis Bullosa
08/2010 - 01/2006
3Neoplasm Metastasis (Metastasis)
10/2022 - 05/2015
3Palmoplantar Keratoderma (Keratosis Palmaris et Plantaris)
01/2022 - 06/2007
3Inborn Genetic Diseases (Disease, Hereditary)
01/2021 - 07/2006
3Dyschromatosis symmetrica hereditaria 1
01/2020 - 03/2014
3Leg Ulcer
11/2019 - 05/2011
3Thrombosis (Thrombus)
10/2019 - 11/2009
2Extramammary Paget Disease (Paget Disease, Extramammary)
10/2022 - 06/2008
2Darier Disease (Darier's Disease)
08/2022 - 03/2015
2Muscular Diseases (Myopathy)
02/2022 - 12/2007
2Hypersensitivity (Allergy)
01/2022 - 11/2018
2Acrodermatitis (Gianotti Crosti Syndrome)
01/2022 - 05/2018
2Netherton Syndrome
05/2021 - 11/2018
2Acute Generalized Exanthematous Pustulosis
04/2021 - 03/2015
2Localized Scleroderma (Morphea)
02/2021 - 01/2017
2Bronchiolitis Obliterans
10/2020 - 08/2020
2Hypotrichosis
10/2020 - 05/2010
2Skin Manifestations
01/2020 - 08/2010
2Pulmonary Eosinophilia (Eosinophilic Pneumonia)
10/2019 - 12/2018
2Chilblain lupus 1
10/2019 - 12/2012
2Dowling-Degos Disease
02/2019 - 09/2013
2Vasculitis (Vasculitides)
02/2019 - 11/2016
2Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders)
12/2018 - 01/2003
2Skin Neoplasms (Skin Cancer)
11/2018 - 09/2016
2Infections
11/2018 - 10/2014
2Keratitis, Ichthyosis, and Deafness (KID) Syndrome
11/2018 - 05/2014

Drug/Important Bio-Agent (IBA)

27AutoantibodiesIBA
02/2022 - 03/2005
23AntibodiesIBA
11/2022 - 06/2008
20LipidsIBA
01/2020 - 11/2003
13Proteins (Proteins, Gene)FDA Link
11/2021 - 07/2003
11Filaggrin ProteinsIBA
01/2020 - 02/2002
8Immune Checkpoint InhibitorsIBA
11/2021 - 01/2016
7Keratins (Keratin)IBA
12/2020 - 02/2002
7Messenger RNA (mRNA)IBA
11/2020 - 05/2003
6DNA (Deoxyribonucleic Acid)IBA
11/2020 - 12/2004
6NivolumabIBA
11/2019 - 01/2016
6Nonsense Codon (Nonsense Mutation)IBA
10/2017 - 12/2006
6Collagen Type XVIIIBA
02/2011 - 03/2007
5EnzymesIBA
11/2017 - 06/2013
4Immunoglobulin E (IgE)IBA
09/2020 - 07/2012
4CeramidesIBA
01/2020 - 10/2017
4Immunoglobulin G (IgG)IBA
05/2018 - 04/2006
4Amino AcidsFDA Link
03/2014 - 06/2007
3Adrenal Cortex Hormones (Corticosteroids)IBA
10/2021 - 10/2013
3apremilastIBA
05/2021 - 12/2019
3secukinumabIBA
01/2021 - 06/2018
3CytokinesIBA
11/2020 - 01/2020
3SteroidsIBA
01/2020 - 12/2018
3von Willebrand FactorIBA
10/2019 - 11/2009
3transcriptional intermediary factor 1IBA
12/2016 - 08/2012
3Hydroxyurea (Hydrea)FDA LinkGeneric
05/2016 - 05/2011
3Collagen Type VIIIBA
11/2012 - 04/2006
3transglutaminase 1IBA
08/2011 - 02/2007
3AntigensIBA
02/2010 - 04/2006
3Keratin-10IBA
07/2008 - 12/2004
2Ligases (Synthetase)IBA
02/2022 - 01/2021
2Granulocyte Colony-Stimulating Factor (G-CSF)IBA
01/2022 - 10/2003
2Cadherins (E-Cadherin)IBA
01/2022 - 11/2018
2Interleukin-1 (Interleukin 1)IBA
01/2022 - 09/2016
2Hydroxychloroquine (Plaquenil)FDA LinkGeneric
09/2021 - 10/2019
2dupilumabIBA
05/2021 - 09/2020
2Amino Acyl-tRNA Synthetases (Aminoacyl-tRNA Synthetase)IBA
01/2021 - 01/2021
2Mutant Proteins (Protein, Mutant)IBA
01/2021 - 06/2015
2LigandsIBA
09/2020 - 01/2016
2pembrolizumabIBA
06/2020 - 04/2020
2IpilimumabIBA
06/2020 - 11/2019
2betamethasone-17,21-dipropionate (betamethasone dipropionate)FDA LinkGeneric
05/2020 - 10/2017
2calcipotriene (calcipotriol)FDA LinkGeneric
05/2020 - 10/2017
2Pharmaceutical PreparationsIBA
10/2019 - 08/2018
2Dichlorodiphenyldichloroethane (DDD)IBA
02/2019 - 09/2013
2AllergensIBA
11/2018 - 03/2011
2CollagenIBA
11/2018 - 03/2010

Therapy/Procedure

20Therapeutics
07/2022 - 12/2006
2Lymph Node Excision (Lymph Node Dissection)
10/2022 - 05/2015